##A suggestion - nothing more

###ISO
The lower your ISO, the less digital noise you will have.  Although modern cameras are improving noise very quickly, I suggest that you start by setting the lowest ISO you have.  

###Shutter
To start out with, you probably don't want any motion blur in your photos, so set the shutter speed at faster than, say 1/50 of a second.  (The rule of thumb is to have the shutter going at least as fast as the length of the lens, so at least 1/50 of a second for a 50mm lens, at least 1/100 of a second for a 100mm lens, etc.)  

###Apperture
This leaves apperture - leave apperture on automatic so that you can get the correct exposure having set the ISO and shutter speeds.  

Try it out and see how it works for you - then have fun changing things.  
When changing settings, it is often best to choose one setting and change that, rather than making lots of alterations at once.