I'd like to aggressively compress some scientific 16-bit grayscale image files, but without reducing the dynamic range. Is such a thing possible?
I understand that JPEG format uses lossy, and therefore tunably aggressive, compression, but only supports 8-bits per color channel.
PNG format supports 16-bit grayscale images, but only supports lossless compression, which limits the file compression ratio.
TIFF format also supports 16-bit grayscale images, but as far as I am aware, supports no standard lossy compression of 16-bit images.