When using Adobe Photoshop or Lightroom for example, and zooming the photo at 1:1 ratio, when you work on a 22" screen at 1680 x 1050, there is an great inside zoom. On such a screen the pixel are large, so they are rendered precisely, and their size allow precise work.
When doing the same thing on a 27" screen at 2560 x 1440, whose pixel are really smaller, I imagine that the zoom is not so important, and it's more difficult to work on the photo. So to have the same comfort, I guess you have to zoom more, someting like 2:1. But doing this, I imaghone that the pixels are more blurry so it's more difficult to work precisely.
What happens in real life ? Do you have some experience on this ? I'm planning to change my 22" screen to a 27" one, but before spending a lot of money, I'd like to have some light on that point.