I have 2 rolls of half-frame film to scan this evening, which amounts to over 144 photos. Most of the manual labor is selecting each photo with the Marquee Tool by hand in the Epson Scan application.
Another alternative is using the "Automatically locates the images" feature (when you untick "Thumbnail" in the main window), which selects automatically two images at the same time. This option is a problem, because Auto Exposure is not working very well when I do it, and file numbering becomes a very complex process to retain the order of the photos:
In the 4th image of this Epson Support link, there seems to be a way to use the Automatically locate the image even outside of Thumbnail mode.
Is there a way to allow the scanner to detect each one of the 22 half-frame photos present in the film holder without the software jamming them together?