Disclaimer: I have not tried a D7000 yet, so I'm answering in general terms.
The only downside I know of is for using Bulb mode on some cameras.
With a cable release: You press the remote button, hold it down and then let go when done. Some remotes have an option to keep the button locked down, but you have to release it at then end of the exposure.
With a wireless release: The principle is the same except that you need to keep aiming at the camera's IR receiver. Otherwise, the camera may interpret the lack of IR signal as closing the shutter. If anything passes between the remote and the IR receiver, it may also happen.
The exact behavior depends on the exact camera. The ideal is that you click once to open the shutter and click again to close it.
On some, there is an option to control the behavior. I know both Pentax K-5 and K-7 (excluding original F/W) have that option.